The Manufacturing Extension Partnership (MEP) contracted with the Upjohn Institute to perform an analysis of the total effect of MEP projects on the U.S. economy. To help improve competitiveness and productivity, MEP centers provide assistance and support to primarily small- and medium-size manufacturing businesses. This study used the REMI model to estimate the indirect and induced effects of the reported increase in jobs, sales, cost savings, and investments by MEP clients. Three scenarios were implemented in this study and the estimates were based on a survey that the National Institute of Standards and Technology (NIST) MEP administers to their clients.